Polygenic hazard scores in preclinical Alzheimer's disease

Polygenic hazard scores in preclinical Alzheimer's disease

Identifying asymptomatic older individuals at elevated risk for developing Alzheimer's disease (AD) is of clinical importance. Among 1,081 asymptomatic older adults, a recently validated polygenic hazard score (PHS) significantly predicted time to AD dementia and steeper longitudinal cognitive...

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Main Authors: TAN, Chin Hong, HYMAN, Bradley T., TAN, Jacinth J. X., HESS, Christopher P., DILLON, William P., SCHELLENBERG, Gerard D., BESSER, Lilah M., KUKULL, Walter A., KAUPPI, Karolina, MCEVOY, Linda K., ANDREASSEN, Ole A., DALE, Anders M., FAN, Chun Chieh, DESIKAN, Rahul S.
Format: text
Language:English
Published: Institutional Knowledge at Singapore Management University 2017
Subjects:
Polygenic risk
Preclinical AD
Diseases
Psychology
Online Access:https://ink.library.smu.edu.sg/soss_research/2744
https://ink.library.smu.edu.sg/context/soss_research/article/4001/viewcontent/Polygenic_hazard_scores_in_preclinical_Alzheimer_d__1_.pdf
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Institution: Singapore Management University
Language: English

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https://ink.library.smu.edu.sg/soss_research/2744
https://ink.library.smu.edu.sg/context/soss_research/article/4001/viewcontent/Polygenic_hazard_scores_in_preclinical_Alzheimer_d__1_.pdf

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