Evaluating spray gelation and spray freeze drying as the granulation method to prepare oral tablets of amorphous drug nanoplex

• المؤلفون الرئيسيون: Chua, Angeline, Ng, He Tong, Cheow, Wean Sin, Hadinoto, Kunn
• مؤلفون آخرون: School of Chemistry, Chemical Engineering and Biotechnology
• التنسيق: مقال
• اللغة: English
• منشور في: 2023
• الموضوعات: Engineering::Bioengineering; Drug Nanoparticles; Amorphous Drugs
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/171395
• المؤسسة: Nanyang Technological University

Amorphous drug nanoplex represents one of the most promising solubility enhancement strategies of poorly-soluble drugs. Solubility enhancement capability of nanoplex hitherto has been demonstrated for nanoplex suspension and lyophilized/spray-dried nanoplex, but not for its oral tablets. Using cipro...