Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest

Guidelines recommend normocapnia for adults with coma who are resuscitated after out-of-hospital cardiac arrest. However, mild hypercapnia increases cerebral blood flow and may improve neurologic outcomes.

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Main Authors: Eastwood, Glenn, Nichol, Alistair D., Hodgson, Carol, Parke, Rachael L., McGuinness, Shay, Nielsen, Niklas, Bernard, Stephen, Skrifvars, Markus B., Stub, Dion, Taccone, Fabio S., Archer, John, Kutsogiannis, Demetrios, Dankiewicz, Josef, Lilja, Gisela, Cronberg, Tobias, Kirkegaard, Hans, Capellier, Gilles, Landoni, Giovanni, Horn, Janneke, Olasveengen, Theresa, Arabi, Yaseen, Chia, Yew Woon, Markota, Andrej, Hænggi, Matthias, Wise, Matt P., Grejs, Anders M., Christensen, Steffen, Munk-Andersen, Heidi, Granfeldt, Asger, Andersen, Geir Ø, Qvigstad, Eirik, Flaa, Arnljot, Thomas, Matthew, Sweet, Katie, Bewley, Jeremy, Bäcklund, Minna, Tiainen, Marjaana, Iten, Manuela, Levis, Anja, Peck, Leah, Walsham, James, Deane, Adam, Ghosh, Angajendra, Annoni, Filippo, Chen, Yan, Knight, David, Lesona, Eden, Tlayjeh, Haytham, Svenšek, Franc, McGuigan, Peter J., Cole, Jade, Pogson, David, Hilty, Matthias P., Düring, Joachim P., Bailey, Michael J., Paul, Eldho, Ady, Bridget, Ainscough, Kate, Hunt, Anna, Monahan, Sinéad, Trapani, Tony, Fahey, Ciara, Bellomo, Rinaldo
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/171503
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spelling sg-ntu-dr.10356-1715032023-11-05T15:39:41Z Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest Eastwood, Glenn Nichol, Alistair D. Hodgson, Carol Parke, Rachael L. McGuinness, Shay Nielsen, Niklas Bernard, Stephen Skrifvars, Markus B. Stub, Dion Taccone, Fabio S. Archer, John Kutsogiannis, Demetrios Dankiewicz, Josef Lilja, Gisela Cronberg, Tobias Kirkegaard, Hans Capellier, Gilles Landoni, Giovanni Horn, Janneke Olasveengen, Theresa Arabi, Yaseen Chia, Yew Woon Markota, Andrej Hænggi, Matthias Wise, Matt P. Grejs, Anders M. Christensen, Steffen Munk-Andersen, Heidi Granfeldt, Asger Andersen, Geir Ø Qvigstad, Eirik Flaa, Arnljot Thomas, Matthew Sweet, Katie Bewley, Jeremy Bäcklund, Minna Tiainen, Marjaana Iten, Manuela Levis, Anja Peck, Leah Walsham, James Deane, Adam Ghosh, Angajendra Annoni, Filippo Chen, Yan Knight, David Lesona, Eden Tlayjeh, Haytham Svenšek, Franc McGuigan, Peter J. Cole, Jade Pogson, David Hilty, Matthias P. Düring, Joachim P. Bailey, Michael J. Paul, Eldho Ady, Bridget Ainscough, Kate Hunt, Anna Monahan, Sinéad Trapani, Tony Fahey, Ciara Bellomo, Rinaldo Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Cardiac Arrest Cardiology Guidelines recommend normocapnia for adults with coma who are resuscitated after out-of-hospital cardiac arrest. However, mild hypercapnia increases cerebral blood flow and may improve neurologic outcomes. Published version Supported by the National Health and Medical Research Council of Australia, the Health Research Board of Ireland, and the Health Research Council of New Zealand. 2023-10-30T00:40:51Z 2023-10-30T00:40:51Z 2023 Journal Article Eastwood, G., Nichol, A. D., Hodgson, C., Parke, R. L., McGuinness, S., Nielsen, N., Bernard, S., Skrifvars, M. B., Stub, D., Taccone, F. S., Archer, J., Kutsogiannis, D., Dankiewicz, J., Lilja, G., Cronberg, T., Kirkegaard, H., Capellier, G., Landoni, G., Horn, J., ...Bellomo, R. (2023). Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest. New England Journal of Medicine, 389(1), 45-57. https://dx.doi.org/10.1056/NEJMoa2214552 0028-4793 https://hdl.handle.net/10356/171503 10.1056/NEJMoa2214552 37318140 2-s2.0-85164131143 1 389 45 57 en New England Journal of Medicine © 2023 Massachusetts Medical Society. All rights reserved. This article may be downloaded for personal use only. Any other use requires prior permission of the copyright holder. The Version of Record is available online at http://doi.org/10.1056/NEJMoa2214552. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Cardiac Arrest
Cardiology
spellingShingle Science::Medicine
Cardiac Arrest
Cardiology
Eastwood, Glenn
Nichol, Alistair D.
Hodgson, Carol
Parke, Rachael L.
McGuinness, Shay
Nielsen, Niklas
Bernard, Stephen
Skrifvars, Markus B.
Stub, Dion
Taccone, Fabio S.
Archer, John
Kutsogiannis, Demetrios
Dankiewicz, Josef
Lilja, Gisela
Cronberg, Tobias
Kirkegaard, Hans
Capellier, Gilles
Landoni, Giovanni
Horn, Janneke
Olasveengen, Theresa
Arabi, Yaseen
Chia, Yew Woon
Markota, Andrej
Hænggi, Matthias
Wise, Matt P.
Grejs, Anders M.
Christensen, Steffen
Munk-Andersen, Heidi
Granfeldt, Asger
Andersen, Geir Ø
Qvigstad, Eirik
Flaa, Arnljot
Thomas, Matthew
Sweet, Katie
Bewley, Jeremy
Bäcklund, Minna
Tiainen, Marjaana
Iten, Manuela
Levis, Anja
Peck, Leah
Walsham, James
Deane, Adam
Ghosh, Angajendra
Annoni, Filippo
Chen, Yan
Knight, David
Lesona, Eden
Tlayjeh, Haytham
Svenšek, Franc
McGuigan, Peter J.
Cole, Jade
Pogson, David
Hilty, Matthias P.
Düring, Joachim P.
Bailey, Michael J.
Paul, Eldho
Ady, Bridget
Ainscough, Kate
Hunt, Anna
Monahan, Sinéad
Trapani, Tony
Fahey, Ciara
Bellomo, Rinaldo
Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
description Guidelines recommend normocapnia for adults with coma who are resuscitated after out-of-hospital cardiac arrest. However, mild hypercapnia increases cerebral blood flow and may improve neurologic outcomes.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Eastwood, Glenn
Nichol, Alistair D.
Hodgson, Carol
Parke, Rachael L.
McGuinness, Shay
Nielsen, Niklas
Bernard, Stephen
Skrifvars, Markus B.
Stub, Dion
Taccone, Fabio S.
Archer, John
Kutsogiannis, Demetrios
Dankiewicz, Josef
Lilja, Gisela
Cronberg, Tobias
Kirkegaard, Hans
Capellier, Gilles
Landoni, Giovanni
Horn, Janneke
Olasveengen, Theresa
Arabi, Yaseen
Chia, Yew Woon
Markota, Andrej
Hænggi, Matthias
Wise, Matt P.
Grejs, Anders M.
Christensen, Steffen
Munk-Andersen, Heidi
Granfeldt, Asger
Andersen, Geir Ø
Qvigstad, Eirik
Flaa, Arnljot
Thomas, Matthew
Sweet, Katie
Bewley, Jeremy
Bäcklund, Minna
Tiainen, Marjaana
Iten, Manuela
Levis, Anja
Peck, Leah
Walsham, James
Deane, Adam
Ghosh, Angajendra
Annoni, Filippo
Chen, Yan
Knight, David
Lesona, Eden
Tlayjeh, Haytham
Svenšek, Franc
McGuigan, Peter J.
Cole, Jade
Pogson, David
Hilty, Matthias P.
Düring, Joachim P.
Bailey, Michael J.
Paul, Eldho
Ady, Bridget
Ainscough, Kate
Hunt, Anna
Monahan, Sinéad
Trapani, Tony
Fahey, Ciara
Bellomo, Rinaldo
format Article
author Eastwood, Glenn
Nichol, Alistair D.
Hodgson, Carol
Parke, Rachael L.
McGuinness, Shay
Nielsen, Niklas
Bernard, Stephen
Skrifvars, Markus B.
Stub, Dion
Taccone, Fabio S.
Archer, John
Kutsogiannis, Demetrios
Dankiewicz, Josef
Lilja, Gisela
Cronberg, Tobias
Kirkegaard, Hans
Capellier, Gilles
Landoni, Giovanni
Horn, Janneke
Olasveengen, Theresa
Arabi, Yaseen
Chia, Yew Woon
Markota, Andrej
Hænggi, Matthias
Wise, Matt P.
Grejs, Anders M.
Christensen, Steffen
Munk-Andersen, Heidi
Granfeldt, Asger
Andersen, Geir Ø
Qvigstad, Eirik
Flaa, Arnljot
Thomas, Matthew
Sweet, Katie
Bewley, Jeremy
Bäcklund, Minna
Tiainen, Marjaana
Iten, Manuela
Levis, Anja
Peck, Leah
Walsham, James
Deane, Adam
Ghosh, Angajendra
Annoni, Filippo
Chen, Yan
Knight, David
Lesona, Eden
Tlayjeh, Haytham
Svenšek, Franc
McGuigan, Peter J.
Cole, Jade
Pogson, David
Hilty, Matthias P.
Düring, Joachim P.
Bailey, Michael J.
Paul, Eldho
Ady, Bridget
Ainscough, Kate
Hunt, Anna
Monahan, Sinéad
Trapani, Tony
Fahey, Ciara
Bellomo, Rinaldo
author_sort Eastwood, Glenn
title Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
title_short Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
title_full Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
title_fullStr Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
title_full_unstemmed Mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
title_sort mild hypercapnia or normocapnia after out-of-hospital cardiac arrest
publishDate 2023
url https://hdl.handle.net/10356/171503
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