Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes

• Main Authors: Martinez, Nuria, Smulan, Lorissa J., Jameson, Michael L., Smith, Clare M., Cavallo, Kelly, Bellerose, Michelle, Williams, John, West, Kim, Sassetti, Christopher M., Singhal, Amit, Kornfeld, Hardy
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Glycerol; Diabetes Mellitus
• Online Access: https://hdl.handle.net/10356/171513
• Institution: Nanyang Technological University

Diabetes mellitus increases risk for tuberculosis disease and adverse outcomes. Most people with both conditions have type 2 diabetes, but it is unknown if type 1 and type 2 diabetes have identical effects on tuberculosis susceptibility. Here we show that male mice receiving a high-fat diet and stre...