Sequence variants affecting voice pitch in humans

• Main Authors: Gisladottir, Rosa S., Helgason, Agnar, Halldorsson, Bjarni V., Helgason, Hannes, Borsky, Michal, Chien, Yu-Ren, Gudnason, Jon, Gudjonsson, Sigurjon A., Moisik, Scott, Dediu, Dan, Thorleifsson, Gudmar, Tragante, Vinicius, Bustamante, Mariana, Jonsdottir, Gudrun A., Stefansdottir, Lilja, Rutsdottir, Gudrun, Magnusson, Sigurdur H., Hardarson, Marteinn, Ferkingstad, Egil, Halldorsson, Gisli H., Rognvaldsson, Solvi, Skuladottir, Astros, Ivarsdottir, Erna V., Norddahl, Gudmundur, Thorgeirsson, Gudmundur, Jonsdottir, Ingileif, Ulfarsson, Magnus O., Holm, Hilma, Stefansson, Hreinn, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Sulem, Patrick, Stefansson, Kari
• Other Authors: School of Humanities
• Format: Article
• Language: English
• Published: 2023
• Subjects: Humanities::Linguistics; Coverage Neanderthal Genome; Vocal Fold Health
• Online Access: https://hdl.handle.net/10356/171686
• Institution: Nanyang Technological University

The genetic basis of the human vocal system is largely unknown, as are the sequence variants that give rise to individual differences in voice and speech. Here, we couple data on diversity in the sequence of the genome with voice and vowel acoustics in speech recordings from 12,901 Icelanders. We sh...