Characterizing amyloid precursor protein (APP) signaling in neural stem cells.

• Main Author: Heese, Klaus.
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• Online Access: http://hdl.handle.net/10356/17215
• Institution: Nanyang Technological University

Alzheimer's disease (AD) is an age-related neurodegenerative disorder that is characterized by irreversible and progressive loss of money and deterioration of higher cognitive functions. The brain of an individual with AD exhibits extracellular senile plaques of aggregated amyloid-beta-peptide...