High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media

Feedback-based wavefront shaping is a promising and versatile technique for enhancing the contrast of a target signal for both coherent and incoherent light through a highly scattering medium. However, this technique can fail for a dynamic sample with a short correlation time. So far, most proposed...

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Main Authors: Hsieh, Chao-Mao, Malik, Mohammad O. A., Liu, Quan
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2023
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Online Access:https://hdl.handle.net/10356/172161
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1721612023-11-28T01:52:29Z High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media Hsieh, Chao-Mao Malik, Mohammad O. A. Liu, Quan School of Chemistry, Chemical Engineering and Biotechnology Engineering::Chemical engineering Scattering Medium Dynamic Scattering Feedback-based wavefront shaping is a promising and versatile technique for enhancing the contrast of a target signal for both coherent and incoherent light through a highly scattering medium. However, this technique can fail for a dynamic sample with a short correlation time. So far, most proposed methods for high-speed wavefront shaping can only directly enhance the intensity of coherent light but not incoherent light. Here we try to fill this gap to directly enhance incoherent light with high speed, such as fluorescence, which is essential in extending wavefront shaping to biomedical applications. For this purpose, we develop a technique based on a single acousto-optic deflector (AOD) with field-programmable gate array (FPGA) acceleration for spatiotemporal focusing within milliseconds. With the digital time gating of the feedback signal, spatiotemporal focusing of laser light with high contrast can be formed behind dynamic scattering media in milliseconds resulting in fluorescence enhancement. Furthermore, FPGA-based wavefront shaping is shown to effectively enhance fluorescence directly behind dynamic samples with short correlation times. Funding: National Natural Science Foundation of China (32250006); Fujian Minjiang Distinguished Scholar Program; Innovation Laboratory for Sciences and Technologies of Energy Materials (IKKEM) of Fujian Province (HRTP-[2022]-46); Ministry of Education (RG129/19, RT16/19). 2023-11-28T01:52:29Z 2023-11-28T01:52:29Z 2023 Journal Article Hsieh, C., Malik, M. O. A. & Liu, Q. (2023). High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media. Optics Letters, 48(9), 2313-2316. https://dx.doi.org/10.1364/OL.491457 0146-9592 https://hdl.handle.net/10356/172161 10.1364/OL.491457 37126262 2-s2.0-85158107231 9 48 2313 2316 en RG129/19 RT16/19 Optics Letters © 2023 Optica Publishing Group. All rights reserved.
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Chemical engineering
Scattering Medium
Dynamic Scattering
spellingShingle Engineering::Chemical engineering
Scattering Medium
Dynamic Scattering
Hsieh, Chao-Mao
Malik, Mohammad O. A.
Liu, Quan
High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
description Feedback-based wavefront shaping is a promising and versatile technique for enhancing the contrast of a target signal for both coherent and incoherent light through a highly scattering medium. However, this technique can fail for a dynamic sample with a short correlation time. So far, most proposed methods for high-speed wavefront shaping can only directly enhance the intensity of coherent light but not incoherent light. Here we try to fill this gap to directly enhance incoherent light with high speed, such as fluorescence, which is essential in extending wavefront shaping to biomedical applications. For this purpose, we develop a technique based on a single acousto-optic deflector (AOD) with field-programmable gate array (FPGA) acceleration for spatiotemporal focusing within milliseconds. With the digital time gating of the feedback signal, spatiotemporal focusing of laser light with high contrast can be formed behind dynamic scattering media in milliseconds resulting in fluorescence enhancement. Furthermore, FPGA-based wavefront shaping is shown to effectively enhance fluorescence directly behind dynamic samples with short correlation times.
author2 School of Chemistry, Chemical Engineering and Biotechnology
author_facet School of Chemistry, Chemical Engineering and Biotechnology
Hsieh, Chao-Mao
Malik, Mohammad O. A.
Liu, Quan
format Article
author Hsieh, Chao-Mao
Malik, Mohammad O. A.
Liu, Quan
author_sort Hsieh, Chao-Mao
title High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
title_short High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
title_full High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
title_fullStr High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
title_full_unstemmed High-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
title_sort high-speed feedback based wavefront shaping for spatiotemporal enhancement of incoherent light through dynamic scattering media
publishDate 2023
url https://hdl.handle.net/10356/172161
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