Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy

• Main Authors: Yang, Li, Zhang, Dan, Li, Wenjing, Lin, Hongbing, Ding, Chendi, Liu, Qingyun, Wang, Liangliang, Li, Zimu, Mei, Lin, Chen, Hongzhong, Zhao, Yanli, Zeng, Xiaowei
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering::Bioengineering; Diabetes Mellitus; Wound Healing
• Online Access: https://hdl.handle.net/10356/172995
• Institution: Nanyang Technological University

The treatment of diabetic wounds faces enormous challenges due to complex wound environments, such as infected biofilms, excessive inflammation, and impaired angiogenesis. The critical role of the microenvironment in the chronic diabetic wounds has not been addressed for therapeutic development. Her...