Curvature-enhanced membrane asymmetry slows down protein diffusion

• Main Authors: Kumar, Jatin, Chng, Choon-Peng, Huang, Changjin
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering::Mechanical engineering; Transmembrane Protein; Lipid Bilayer
• Online Access: https://hdl.handle.net/10356/173064
• Institution: Nanyang Technological University

Diffusion of transmembrane proteins plays a vital role in various cellular processes, such as endocytosis, raft formation and signal transduction. Current understanding of protein diffusion dynamics in lipid membranes is mostly based on hydrodynamic analyses, in which lipid membrane is simply treate...