A mechanism-based theory of cellular and tissue plasticity

• Main Authors: Sun, Fuqiang, Fang, Chao, Shao, Xueying, Gao, Huajian, Lin, Yuan
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering::Mechanical engineering; Cell Plasticity; Endocytosis
• Online Access: https://hdl.handle.net/10356/173208
• Institution: Nanyang Technological University

Plastic deformation in cells and tissues has been found to play crucial roles in collective cell migration, cancer metastasis, and morphogenesis. However, the fundamental question of how plasticity is initiated in individual cells and then propagates within the tissue remains elusive. Here, we devel...