Understanding early molecular mechanisms of abnormal myelination in neurological conditions by characterising Ermin deficiency

• Main Authors: Oh, Sher Li, Ziaei, Amin, Tan, Liang Juin, Utami, Kagistia Hana, Pouladi, Mahmoud A., Langley, Sarah Raye
• Other Authors: Interdisciplinary Graduate School (IGS)
• Format: Conference or Workshop Item
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Neurological disorders; Ermin deficiency
• Online Access: https://hdl.handle.net/10356/173229; https://www.grc.org/myelin-conference/2024/
• Institution: Nanyang Technological University

Abnormal myelination has been observed across several neurodegenerative conditions, and is hypothesised to be a key factor leading to disease pathophysiology. Here, we investigate early molecular mechanisms leading to abnormal myelination using Ermin deficiency as a model. Ermin is a gene expressed...