Buccal delivery system of active pharmaceutical ingredients-ionic liquid (API-IL): effects of API-IL loading and gelatin film concentration

• Main Authors: Ng, Liu Han, Hadinoto, Kunn
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering::Chemical engineering; Drug Delivery System; Poorly Soluble Drugs
• Online Access: https://hdl.handle.net/10356/173236
• Institution: Nanyang Technological University

Ionic liquid (IL) salt of active pharmaceutical ingredient (API) represents a promising formulation strategy to address low drug solubility and polymorphism prevalent in API solid crystals. The present work developed for the first time a buccal delivery system of API-IL via fast-dissolving API-IL-lo...