Comparative secretome metabolic dysregulation by six engineered dietary nanoparticles (EDNs) on the simulated gut microbiota

• Main Authors: Fan, Yijun, Keerthisinghe, Tharushi Prabha, Nian, Min, Cao, Xiaoqiong, Chen, Xing, Yang, Qin, Sampathkumar, Kaarunya, Loo, Joachim Say Chye, Ng, Kee Woei, Demokritou, Philip, Fang, Mingliang
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering::Materials; Engineered Dietary Nanoparticles; Gut Microbiota
• Online Access: https://hdl.handle.net/10356/173245
• Institution: Nanyang Technological University

The potential use of engineered dietary nanoparticles (EDNs) in diet has been increasing and poses a risk of exposure. The effect of EDNs on gut bacterial metabolism remains largely unknown. In this study, liquid chromatography-mass spectrometry (LC-MS) based metabolomics was used to reveal signific...