Semiconducting polymer nanospherical nucleic acid probe for transcriptomic imaging of cancer chemo-immunotherapy

• المؤلفون الرئيسيون: Xu, Cheng, Yu, Jie, Ning, Xiaoyu, Xu, Mengke, He, Shasha, Wu, Jiayan, Pu, Kanyi
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Science::Medicine; Engineering::Bioengineering; Cancer Immunotherapy; Fluorescence Imaging
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/173281

Real-time in vivo imaging of RNA can enhance the understanding of physio-pathological processes. However, most nucleic acid-based sensors have poor resistance to nucleases and limited photophysical properties, making them suboptimal for this purpose. To address this, a semiconducting polymer nanosph...