Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)

The Global Parkinson's Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for c...

Full description

Saved in:

Bibliographic Details
Main Authors:	Towns, Clodagh, Richer, Madeleine, Jasaityte, Simona, Stafford, Eleanor J., Joubert, Julie, Antar, Tarek, Martinez-Carrasco, Alejandro, Makarious, Mary B., Casey, Bradford, Vitale, Dan, Levine, Kristin, Leonard, Hampton, Pantazis, Caroline B., Screven, Laurel A., Hernandez, Dena G., Wegel, Claire E., Solle, Justin, Nalls, Mike A., Blauwendraat, Cornelis, Singleton, Andrew B., Tan, Manuela M. X., Iwaki, Hirotaka, Morris, Huw R., Foo, Jia Nee
Other Authors:	Lee Kong Chian School of Medicine (LKCMedicine)
Format:	Article
Language:	English
Published:	2024
Subjects:	Medicine, Health and Life Sciences Cerebrospinal Fluid Parkinson Disease
Online Access:	https://hdl.handle.net/10356/173527
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-173527
record_format	dspace
spelling	sg-ntu-dr.10356-1735272024-02-18T15:37:52Z Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2) Towns, Clodagh Richer, Madeleine Jasaityte, Simona Stafford, Eleanor J. Joubert, Julie Antar, Tarek Martinez-Carrasco, Alejandro Makarious, Mary B. Casey, Bradford Vitale, Dan Levine, Kristin Leonard, Hampton Pantazis, Caroline B. Screven, Laurel A. Hernandez, Dena G. Wegel, Claire E. Solle, Justin Nalls, Mike A. Blauwendraat, Cornelis Singleton, Andrew B. Tan, Manuela M. X. Iwaki, Hirotaka Morris, Huw R. Foo, Jia Nee Lee Kong Chian School of Medicine (LKCMedicine) Medicine, Health and Life Sciences Cerebrospinal Fluid Parkinson Disease The Global Parkinson's Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia. Published version This research is supported by the Aligning Science Across Parkinson’s Initiative, the Intramural Research Program, National Institute on Aging, National Institutes of Health, Department of Health and Human Services, project ZO1 AG000949, and the Michael J. Fox Foundation for Parkinson’s Research. Data used in the preparation of this article were obtained from Global Parkinson’s Genetics Program (GP2). GP2 is funded by the Aligning Science Across Parkinson’s (ASAP) initiative and implemented by The Michael J. Fox Foundation for Parkinson’s Research (https://gp2.org). 2024-02-13T01:14:34Z 2024-02-13T01:14:34Z 2023 Journal Article Towns, C., Richer, M., Jasaityte, S., Stafford, E. J., Joubert, J., Antar, T., Martinez-Carrasco, A., Makarious, M. B., Casey, B., Vitale, D., Levine, K., Leonard, H., Pantazis, C. B., Screven, L. A., Hernandez, D. G., Wegel, C. E., Solle, J., Nalls, M. A., Blauwendraat, C., ...Foo, J. N. (2023). Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2). NPJ Parkinson's Disease, 9(1), 131-. https://dx.doi.org/10.1038/s41531-023-00533-w 2373-8057 https://hdl.handle.net/10356/173527 10.1038/s41531-023-00533-w 37699923 2-s2.0-85170643330 1 9 131 en NPJ Parkinson's Disease © 2023 The Author(s). Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http:// creativecommons.org/licenses/by/4.0/. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Medicine, Health and Life Sciences Cerebrospinal Fluid Parkinson Disease
spellingShingle	Medicine, Health and Life Sciences Cerebrospinal Fluid Parkinson Disease Towns, Clodagh Richer, Madeleine Jasaityte, Simona Stafford, Eleanor J. Joubert, Julie Antar, Tarek Martinez-Carrasco, Alejandro Makarious, Mary B. Casey, Bradford Vitale, Dan Levine, Kristin Leonard, Hampton Pantazis, Caroline B. Screven, Laurel A. Hernandez, Dena G. Wegel, Claire E. Solle, Justin Nalls, Mike A. Blauwendraat, Cornelis Singleton, Andrew B. Tan, Manuela M. X. Iwaki, Hirotaka Morris, Huw R. Foo, Jia Nee Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
description	The Global Parkinson's Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia.
author2	Lee Kong Chian School of Medicine (LKCMedicine)
author_facet	Lee Kong Chian School of Medicine (LKCMedicine) Towns, Clodagh Richer, Madeleine Jasaityte, Simona Stafford, Eleanor J. Joubert, Julie Antar, Tarek Martinez-Carrasco, Alejandro Makarious, Mary B. Casey, Bradford Vitale, Dan Levine, Kristin Leonard, Hampton Pantazis, Caroline B. Screven, Laurel A. Hernandez, Dena G. Wegel, Claire E. Solle, Justin Nalls, Mike A. Blauwendraat, Cornelis Singleton, Andrew B. Tan, Manuela M. X. Iwaki, Hirotaka Morris, Huw R. Foo, Jia Nee
format	Article
author	Towns, Clodagh Richer, Madeleine Jasaityte, Simona Stafford, Eleanor J. Joubert, Julie Antar, Tarek Martinez-Carrasco, Alejandro Makarious, Mary B. Casey, Bradford Vitale, Dan Levine, Kristin Leonard, Hampton Pantazis, Caroline B. Screven, Laurel A. Hernandez, Dena G. Wegel, Claire E. Solle, Justin Nalls, Mike A. Blauwendraat, Cornelis Singleton, Andrew B. Tan, Manuela M. X. Iwaki, Hirotaka Morris, Huw R. Foo, Jia Nee
author_sort	Towns, Clodagh
title	Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
title_short	Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
title_full	Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
title_fullStr	Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
title_full_unstemmed	Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
title_sort	defining the causes of sporadic parkinson's disease in the global parkinson's genetics program (gp2)
publishDate	2024
url	https://hdl.handle.net/10356/173527
_version_	1794549285480562688

Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)

Similar Items