Characterizing antibody responses to mosquito salivary antigens of the Southeast Asian vectors of malaria and dengue with a human challenge model of controlled exposure: a protocol

• Main Authors: Sawasdichai, Sunisa, Chaumeau, Victor, Kearney, Ellen, Wasisakun, Praphan, Simpson, Julie A., Price, David J., Chotirat, Sadudee, Rénia, Laurent, Bergmann-Leitner, Elke, Fowkes, Freya, Nosten, François
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Malaria; Dengue
• Online Access: https://hdl.handle.net/10356/173607
• Institution: Nanyang Technological University

Background: Measurement of antibody titers directed against mosquito salivary antigens in blood samples has been proposed as an outcome measure to assess human exposure to vector bites. However, only a handful of antigens have been identified and the specificity and longitudinal dynamics of antibody...