Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: integration of herbal medicine, enzyme engineering, and nanotechnology

• Main Authors: Lu, Yi, Luo, Qiulan, Jia, Xiaobin, Tam, James P., Yang, Huan, Shen, Yuping, Li, Xin
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Flavonoids; Enzymatic hydrolysis
• Online Access: https://hdl.handle.net/10356/173721
• Institution: Nanyang Technological University

Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly, in 2022, icaritin soft capsules were approved to reach the market for the treatment of hepatocellular carcinoma (HCC) by N...