Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1

• Main Authors: La Torre, Mattia, Centofante, Eleonora, Nicoletti, Carmine, Burla, Romina, Giampietro, Alessandro, Cannistrà, Federica, Schirone, Leonardo, Valenti, Valentina, Sciarretta, Sebastiano, Musarò, Antonio, Saggio, Isabella
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Cardiomyopathy; DNA damage
• Online Access: https://hdl.handle.net/10356/173855
• Institution: Nanyang Technological University

DNA damage is emerging as a driver of heart disease, although the cascade of events, its timing, and the cell types involved are yet to be fully clarified. In this context, the implication of cardiomyocytes has been highlighted, while that of vasculature smooth muscle cells has been implicated but n...