BNT162b2 vaccine induced variant-specific immunity, safety and risk of Omicron breakthrough infection in children aged 5 to 11 years: a cohort study

• Main Authors: Yung, Chee Fu, Le Bert, Nina, Kam, Kai Qian, Saffari, Seyed Ehsan, Tan, Chee Wah, Mah, Yun Yan, Zhang, Jinyan, Yeoh, Aileen Ying-Yan, Zhu, Feng, Hariharaputran, Smrithi, Chong, Chia Yin, Bertoletti, Antonio, Wang, Linfa
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; COVID-19; Breakthrough infection
• Online Access: https://hdl.handle.net/10356/173890
• Institution: Nanyang Technological University

There is little information on BNT162b2 vaccine-induced variant-specific immunogenicity, safety data and dynamics of breakthrough infections in pediatric populations. We addressed these questions using a prospective two dose BNT162b2 (10 mcg) vaccination cohort study of healthy children 5-11 years i...