Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs
During the COVID-19 pandemic in Qatar, many patients who were severely ill were colonized and infected by Candida auris, an invasive multidrug-resistant yeast pathogen that spreads through nosocomial transmission within healthcare facilities. Here, we investigated the molecular epidemiology of these...
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sg-ntu-dr.10356-1740582024-06-27T01:37:00Z Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs Abid, Fatma Ben Salah, Husam Sundararaju, Sathyavathi Dalil, Lamya Abdelwahab, Ayman H. Salameh, Sarah Ibrahim, Emad B. Almaslmani, Muna A. Tang, Patrick Perez-Lopez, Andres Tsui, Clement Kin-Ming Lee Kong Chian School of Medicine (LKCMedicine) National Center for Infectious Diseases Medicine, Health and Life Sciences Candida auris COVID-19 During the COVID-19 pandemic in Qatar, many patients who were severely ill were colonized and infected by Candida auris, an invasive multidrug-resistant yeast pathogen that spreads through nosocomial transmission within healthcare facilities. Here, we investigated the molecular epidemiology of these C. auris isolates and the mechanisms associated with antifungal drug resistance. Published version This study was funded by the Sidra Medicine Internal Research Grant (SDR_200052 to A.P.-L. and K.M.T.) and supported by the Medical Research Centre at Hamad Medical Corporation (MRC01019-420 to F.B.A.). 2024-03-13T01:44:15Z 2024-03-13T01:44:15Z 2023 Journal Article Abid, F. B., Salah, H., Sundararaju, S., Dalil, L., Abdelwahab, A. H., Salameh, S., Ibrahim, E. B., Almaslmani, M. A., Tang, P., Perez-Lopez, A. & Tsui, C. K. (2023). Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs. Clinical Microbiology and Infection, 29(8), 1083.e1-1083.e7. https://dx.doi.org/10.1016/j.cmi.2023.04.025 1198-743X https://hdl.handle.net/10356/174058 10.1016/j.cmi.2023.04.025 37116861 2-s2.0-85160342775 8 29 1083.e1 1083.e7 en Clinical Microbiology and Infection © 2023 The Authors. Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf |
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Medicine, Health and Life Sciences Candida auris COVID-19 |
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Medicine, Health and Life Sciences Candida auris COVID-19 Abid, Fatma Ben Salah, Husam Sundararaju, Sathyavathi Dalil, Lamya Abdelwahab, Ayman H. Salameh, Sarah Ibrahim, Emad B. Almaslmani, Muna A. Tang, Patrick Perez-Lopez, Andres Tsui, Clement Kin-Ming Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| description |
During the COVID-19 pandemic in Qatar, many patients who were severely ill were colonized and infected by Candida auris, an invasive multidrug-resistant yeast pathogen that spreads through nosocomial transmission within healthcare facilities. Here, we investigated the molecular epidemiology of these C. auris isolates and the mechanisms associated with antifungal drug resistance. |
| author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Abid, Fatma Ben Salah, Husam Sundararaju, Sathyavathi Dalil, Lamya Abdelwahab, Ayman H. Salameh, Sarah Ibrahim, Emad B. Almaslmani, Muna A. Tang, Patrick Perez-Lopez, Andres Tsui, Clement Kin-Ming |
| format |
Article |
| author |
Abid, Fatma Ben Salah, Husam Sundararaju, Sathyavathi Dalil, Lamya Abdelwahab, Ayman H. Salameh, Sarah Ibrahim, Emad B. Almaslmani, Muna A. Tang, Patrick Perez-Lopez, Andres Tsui, Clement Kin-Ming |
| author_sort |
Abid, Fatma Ben |
| title |
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| title_short |
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| title_full |
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| title_fullStr |
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| title_full_unstemmed |
Molecular characterization of Candida auris outbreak isolates in Qatar from patients with COVID-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| title_sort |
molecular characterization of candida auris outbreak isolates in qatar from patients with covid-19 reveals the emergence of isolates resistant to three classes of antifungal drugs |
| publishDate |
2024 |
| url |
https://hdl.handle.net/10356/174058 |
| _version_ |
1814047176989343744 |