An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles

• Main Authors: Bresalier, Robert S., Senore, Carlo, Young, Graeme P., Allison, James, Benamouzig, Robert, Benton, Sally, Bossuyt, Patrick M. M., Caro, Luis, Carvalho, Beatriz, Chiu, Han-Mo, Coupé, Veerle M. H., de Klaver, Willemijn, de Klerk, Clasine Maria, Dekker, Evelien, Dolwani, Sunil, Fraser, Callum G., Grady, William, Guittet, Lydia, Gupta, Samir, Halloran, Stephen P., Haug, Ulrike, Hoff, Geir, Itzkowitz, Steven, Kortlever, Tim, Koulaouzidis, Anastasios, Ladabaum, Uri, Lauby-Secretan, Beatrice, Leja, Mārcis, Levin, Bernard, Levin, Theodore Robert, Macrae, Finlay, Meijer, Gerrit A., Melson, Joshua, O'Morain, Colm, Parry, Susan, Rabeneck, Linda, Ransohoff, David F., Sáenz, Roque, Saito, Hiroshi, Sanduleanu-Dascalescu, Silvia, Schoen, Robert E., Selby, Kevin, Singh, Harminder, Steele, Robert J. C., Sung, Joseph Jao Yiu, Symonds, Erin Leigh, Winawer, Sidney J.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Colorectal adenomas; Colorectal cancer
• Online Access: https://hdl.handle.net/10356/174162
• Institution: Nanyang Technological University

Objective: New screening tests for colorectal cancer (CRC) are rapidly emerging. Conducting trials with mortality reduction as the end point supporting their adoption is challenging. We re-examined the principles underlying evaluation of new non-invasive tests in view of technological developments a...