Ingestible artificial urinary biomarker probes for urine test of gastrointestinal cancer

• Main Authors: Xu, Cheng, Xu, Mengke, Hu, Yuxuan, Liu, Jing, Cheng, Penghui, Zeng, Ziling, Pu, Kanyi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Bioorthogonal reaction; Cancer detection
• Online Access: https://hdl.handle.net/10356/174214
• Institution: Nanyang Technological University

Although colorectal cancer diagnosed at an early stage shows high curability, methods simultaneously possessing point-of-care testing ability and high sensitivity are limited. Here, an orally deliverable biomarker-activatable probe (termed as HATS) for early detection of orthotopic tumors via remote...