Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid

• المؤلفون الرئيسيون: Wei, Wenchao, Wong, Chi Chun, Jia, Zhongjun, Liu, Weixin, Liu, Changan, Ji, Fenfen, Pan, Yasi, Wang, Feixue, Wang, Guoping, Zhao, Liuyang, Chu, Eagle S. H., Zhang, Xiang, Sung, Joseph Jao Yiu, Yu, Jun
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Medicine, Health and Life Sciences; Insulin; Pentadecanoic acid
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/174263
• المؤسسة: Nanyang Technological University

Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease, and is characterized by liver inflammation and fat accumulation. Dietary interventions, such as fibre, have been shown to alleviate this metabolic disorder in mice via the gut microbiota. Here, we investiga...