Label-free single microparticles and cell aggregates sorting in continuous cell-based manufacturing

• Main Authors: Gong, Lingyan, He, Linwei, Lu, Nan, Petchakup, Chayakorn, Li, Holden King Ho, Tay, Chor Yong, Hou, Han Wei
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Cell-based manufacturing; Hydrogel microparticles
• Online Access: https://hdl.handle.net/10356/174671
• Institution: Nanyang Technological University

There is a paradigm shift in biomanufacturing toward continuous bioprocessing but cell-based manufacturing using adherent and suspension cultures, including microcarriers, hydrogel microparticles, and 3D cell aggregates, remains challenging due to the lack of efficient in-line bioprocess monitoring...