Metabolic nanoregulator remodels gut microenvironment for treatment of inflammatory bowel disease

• Main Authors: Xu, Ting, Ning, Xiaogang, Wu, Jiayan, Wang, Qian, Wang, Zhifei, Chen, Zhiqing, Tang, Xiaoxian, Bai, Peirong, Pu, Kanyi, Li, Liping, Zhang, Ruiping
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Inflammatory bowel disease; Metabolic regulation
• Online Access: https://hdl.handle.net/10356/174695
• Institution: Nanyang Technological University

Inflammatory bowel disease (IBD) is strongly related to the occurrence of accumulation of toxic reactive oxygen species (ROS), inflammation of the mucosa, and an imbalance of intestinal microbes. However, current treatments largely focus on a single factor, yielding unsatisfactory clinical outcomes....