Manipulation of G-quadruplex nanostructures using sequence engineering and chemical modifications: towards development of functional G-quadruplex scaffolds
G-quadruplexes (G4s) are four stranded non-canonical nucleic acid structures made up of guanine (G) rich sequences. These structures are shown to exist inside the cells and play important roles in various crucial processes like gene expression, DNA replication, transcription and translation. Synthet...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2024
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| Online Access: | https://hdl.handle.net/10356/174782 |
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| Institution: | Nanyang Technological University |
| Language: | English |