Tissue ablation with multi-millimeter depth and cellular-scale collateral damage by a femtosecond mid-infrared laser tuned to the amide-I vibration

• Main Authors: Tian, Kan, Xiang, Maoxing, Wen, Xiangyi, Guo, Jinmiao, He, Linzhen, Yu, Peng, Han, Jinghua, Peng, Xu, Wang, Fan, Zhang, Lidan, Fu, Zhizhuo, Chen, Pengfan, Xie, Jing, Wang, Zhenzhou, Wan, Zhongjun, Li, Wenkai, Hu, Bo, Wang, Weizhe, Yang, Xuemei, Ding, Chunmei, Liu, Yuan, Zeng, Yi, Li, Yang, Wu, Han, He, Changtao, Feng, Guoying, Peng, Yujie, Jiang, Xian, Li, Jianshu, Wang, Qi Jie, Zhao, Shengyu, Leng, Yuxin, Liang, Houkun
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Medicine, Health and Life Sciences; Physics; Femtosecond laser; Mid-infrared
• Online Access: https://hdl.handle.net/10356/174939
• Institution: Nanyang Technological University

Laser ablation of bio-tissues is the key technology of future surgeries, owing to the merits of submicron accuracy, non-contact operation, and precision control assisted by automation and computer intelligence. Excellent efficiency, minimal collateral damage, biological safety, and tissue selectivit...