Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment

• Main Authors: Tang, Tao, Zhao, Hao, Shen, Shaofei, Yang, Like, Lim, Chwee Teck
• Other Authors: Department of Biomedical Engineering, NUS
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Cell Suspension; Droplet microfluidics
• Online Access: https://hdl.handle.net/10356/174970
• Institution: Nanyang Technological University

Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing performance. In this study, we introduce a novel droplet microfluidic chip to overcome this challenge. The chip comprises a double spiral focusing unit, a flow...