PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan

• Main Authors: Alfatah, Mohammad, Zhang, Yizhong, Naaz, Arshia, Cheng, Trishia Yi Ning, Eisenhaber, Frank
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Chronological lifespan; High-throughput methods
• Online Access: https://hdl.handle.net/10356/175591
• Institution: Nanyang Technological University

Gerontology research on anti-aging interventions with drugs could be an answer to age-related diseases, aiming at closing the gap between lifespan and healthspan. Here, we present two methods for assaying chronological lifespan in human cells: (1) a version of the classical outgrowth assay with quan...