Functional meniscus reconstruction with biological and biomechanical heterogeneities through topological self-induction of stem cells

• Main Authors: Du, Mingze, Liu, Kangze, Lai, Huinan, Qian, Jin, Ai, Liya, Zhang, Jiying, Yin, Jun, Jiang, Dong
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Tissue-engineered meniscus; Functional reconstruction
• Online Access: https://hdl.handle.net/10356/175603
• Institution: Nanyang Technological University

Meniscus injury is one of the most common sports injuries within the knee joint, which is also a crucial pathogenic factor for osteoarthritis (OA). The current meniscus substitution products are far from able to restore meniscal biofunctions due to the inability to reconstruct the gradient heterogen...