Core-shell microencapsulation of hematopoietic stem cells for the optimisation of lentiviral gene delivery using microfluidics

• Main Author: Sun, Qinglu
• Other Authors: Dalton Tay Chor Yong
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2024
• Subjects: Engineering; Biomaterials
• Online Access: https://hdl.handle.net/10356/175872
• Institution: Nanyang Technological University

This project employed an aqueous two-phase system and double-emulsion method (water-in-water-in-oil) to synthesize microcapsules for encapsulation of hematopoietic stem cells (HSCs) and lentivirus (LVs) with a custom-made microfluidic platform, and the synthesis process was optimized. Two biocompati...