Diazirine cytotoxicity analysis

This paper compares and evaluates the cytotoxicity effects of novel diazirines such as (Trifluoromethyl)-3H-diazirin-3-yl] benzoic acid (Dz-COOH) and 4-3-(Trifluoromethyl) -3H-diazirin-3-yl] benzyl alcohol, CAS# 87736-88-7, (Dz-OH), with commercially available photoinitiators diphenyl (2,4,6-trimeth...

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Bibliographic Details
Main Author: Nur Fazeela D/O Iqbaldeen
Other Authors: Terry W.J. Steele
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/176589
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Institution: Nanyang Technological University
Language: English
Description
Summary:This paper compares and evaluates the cytotoxicity effects of novel diazirines such as (Trifluoromethyl)-3H-diazirin-3-yl] benzoic acid (Dz-COOH) and 4-3-(Trifluoromethyl) -3H-diazirin-3-yl] benzyl alcohol, CAS# 87736-88-7, (Dz-OH), with commercially available photoinitiators diphenyl (2,4,6-trimethyl benzoyl) phosphine oxide, CAS# 75980-60-8, (TPO) and 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone, CAS# 106797-53-9 (Irgacure 2959). This comparative analysis seeks to understand the potential cytotoxicity profiles of these compounds, to ensure safe application in various biomedical applications.