Transethosome-based topical administration systems with enhanced penetration and dual actions for treating EGFR-overexpressed cutaneous squamous cell carcinoma

• Main Authors: Wang, Wenyan, Tham, Phoebe Huijun, Ding, Chendi, Huang, Ping, Li, Tingxuan, Luo, Jingjing, Xiang, Huijing, Zeng, Xiaowei, Chen, Hongzhong, Zhao, Yanli
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Cutaneous squamous cell carcinoma; EGFR inhibitor
• Online Access: https://hdl.handle.net/10356/177932
• Institution: Nanyang Technological University

Epidermal growth factor receptor (EGFR)-overexpressing cutaneous squamous cell carcinoma (CSCC) necessitates more effective therapies due to its elevated metastasis risk compared to the conventional CSCC. While photodynamic therapy (PDT) is a promising way to treat CSCC, effectively administering ph...