Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture

Federated learning (FL) is a distributed machine learning framework that is gaining traction in view of increasing health data privacy protection needs. By conducting a systematic review of FL applications in healthcare, we identify relevant articles in scientific, engineering, and medical journals...

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Main Authors: Teo, Zhen Ling, Jin, Liyuan, Li, Siqi, Miao, Di, Zhang, Xiaoman, Ng, Wei Yan, Tan, Ting Fang, Lee, Deborah Meixuan, Chua, Kai Jie, Heng, John, Liu, Yong, Goh, Rick Siow Mong, Ting, Daniel Shu Wei
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2024
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Online Access:https://hdl.handle.net/10356/178493
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1784932024-06-30T15:39:22Z Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture Teo, Zhen Ling Jin, Liyuan Li, Siqi Miao, Di Zhang, Xiaoman Ng, Wei Yan Tan, Ting Fang Lee, Deborah Meixuan Chua, Kai Jie Heng, John Liu, Yong Goh, Rick Siow Mong Ting, Daniel Shu Wei Lee Kong Chian School of Medicine (LKCMedicine) Singapore Eye Research Institute Medicine, Health and Life Sciences Artificial intelligence Federated learning Federated learning (FL) is a distributed machine learning framework that is gaining traction in view of increasing health data privacy protection needs. By conducting a systematic review of FL applications in healthcare, we identify relevant articles in scientific, engineering, and medical journals in English up to August 31st, 2023. Out of a total of 22,693 articles under review, 612 articles are included in the final analysis. The majority of articles are proof-of-concepts studies, and only 5.2% are studies with real-life application of FL. Radiology and internal medicine are the most common specialties involved in FL. FL is robust to a variety of machine learning models and data types, with neural networks and medical imaging being the most common, respectively. We highlight the need to address the barriers to clinical translation and to assess its real-world impact in this new digital data-driven healthcare scene. Agency for Science, Technology and Research (A*STAR) National Medical Research Council (NMRC) Published version This work was supported by the National Medical Research Council, Singapore (MOH-000655-00 and MOH-001014-00), Duke-NUS Medical School (DukeNUS/RSF/2021/0018 and 05/FY2020/EX/15-A58), and the Agency for Science, Technology, and Research (A20H4g2141 and H20C6a0032). 2024-06-24T06:17:45Z 2024-06-24T06:17:45Z 2024 Journal Article Teo, Z. L., Jin, L., Li, S., Miao, D., Zhang, X., Ng, W. Y., Tan, T. F., Lee, D. M., Chua, K. J., Heng, J., Liu, Y., Goh, R. S. M. & Ting, D. S. W. (2024). Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture. Cell Reports Medicine, 5(2), 101419-. https://dx.doi.org/10.1016/j.xcrm.2024.101419 2666-3791 https://hdl.handle.net/10356/178493 10.1016/j.xcrm.2024.101419 38340728 2-s2.0-85185398686 2 5 101419 en MOH-000655-00 MOH-001014-00 DukeNUS/RSF/2021/0018 05/FY2020/EX/15-A58 A20H4g2141 H20C6a0032 Cell Reports Medicine © 2024 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Medicine, Health and Life Sciences
Artificial intelligence
Federated learning
spellingShingle Medicine, Health and Life Sciences
Artificial intelligence
Federated learning
Teo, Zhen Ling
Jin, Liyuan
Li, Siqi
Miao, Di
Zhang, Xiaoman
Ng, Wei Yan
Tan, Ting Fang
Lee, Deborah Meixuan
Chua, Kai Jie
Heng, John
Liu, Yong
Goh, Rick Siow Mong
Ting, Daniel Shu Wei
Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
description Federated learning (FL) is a distributed machine learning framework that is gaining traction in view of increasing health data privacy protection needs. By conducting a systematic review of FL applications in healthcare, we identify relevant articles in scientific, engineering, and medical journals in English up to August 31st, 2023. Out of a total of 22,693 articles under review, 612 articles are included in the final analysis. The majority of articles are proof-of-concepts studies, and only 5.2% are studies with real-life application of FL. Radiology and internal medicine are the most common specialties involved in FL. FL is robust to a variety of machine learning models and data types, with neural networks and medical imaging being the most common, respectively. We highlight the need to address the barriers to clinical translation and to assess its real-world impact in this new digital data-driven healthcare scene.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Teo, Zhen Ling
Jin, Liyuan
Li, Siqi
Miao, Di
Zhang, Xiaoman
Ng, Wei Yan
Tan, Ting Fang
Lee, Deborah Meixuan
Chua, Kai Jie
Heng, John
Liu, Yong
Goh, Rick Siow Mong
Ting, Daniel Shu Wei
format Article
author Teo, Zhen Ling
Jin, Liyuan
Li, Siqi
Miao, Di
Zhang, Xiaoman
Ng, Wei Yan
Tan, Ting Fang
Lee, Deborah Meixuan
Chua, Kai Jie
Heng, John
Liu, Yong
Goh, Rick Siow Mong
Ting, Daniel Shu Wei
author_sort Teo, Zhen Ling
title Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
title_short Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
title_full Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
title_fullStr Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
title_full_unstemmed Federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
title_sort federated machine learning in healthcare: a systematic review on clinical applications and technical architecture
publishDate 2024
url https://hdl.handle.net/10356/178493
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