Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography

• Main Authors: Tan, Bingyao, Li, Huakun, Zhuo, Yueming, Han, Le, Mupparapu, Rajeshkumar, Nanni, Davide, Barathi, Veluchamy Amutha, Palanker, Daniel, Schmetterer, Leopold, Ling, Tong
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Optoretinography; Optical coherence tomography
• Online Access: https://hdl.handle.net/10356/178508
• Institution: Nanyang Technological University

Phototransduction involves changes in concentration of ions and other solutes within photoreceptors and in subretinal space, which affect osmotic pressure and the associated water flow. Corresponding expansion and contraction of cellular layers can be imaged using optoretinography (ORG), based on ph...