Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore

• Main Authors: Lim, Jue Tao, Bansal, Somya, Chong, Chee Seng, Dickens, Borame, Ng, Youming, Deng, Lu, Lee, Caleb, Tan, Li Yun, Chain, Grace, Ma, Pei, Sim, Shuzhen, Tan, Cheong Huat, Cook, Alex R., Ng, Lee Ching
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Wolbachia; Dengue
• Online Access: https://hdl.handle.net/10356/178612
• Institution: Nanyang Technological University

Background: Due to the absence of available therapeutics and good vaccines, vector control solutions are needed to mitigate the spread of dengue. Matings between male Aedes aegypti mosquitoes infected with the wAlbB strain of Wolbachia and wildtype females yield non-viable eggs. We evaluated the eff...