A tandem-locked chemiluminescent probe for imaging of tumor-associated macrophage polarization

• Main Authors: Huang, Jingsheng, Xu, Mengke, Cheng, Penghui, Yu, Jie, Wu, Jiayan, Pu, Kanyi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Chemistry; Infrared devices; Tumors
• Online Access: https://hdl.handle.net/10356/178894
• Institution: Nanyang Technological University

Tumor-associated macrophages (TAMs) play a role in both pro- and anti-tumor functions; and the targeted polarization from M2 to M1 TAMs has become an effective therapy option. Although detection of M1 TAMs is imperative to assess cancer immunotherapeutic efficacy, existing optical probes suffer from...