Design, synthesis, and antifungal activity of acrylamide derivatives containing trifluoromethylpyridine and piperazine

• المؤلفون الرئيسيون: Chen, Jinli, Zhang, Meng, Yuan, Chunmei, Zhang, Tao, Wu, Zhibing, Li, Tingting, Chi, Robin Yonggui
• مؤلفون آخرون: School of Chemistry, Chemical Engineering and Biotechnology
• التنسيق: مقال
• اللغة: English
• منشور في: 2024
• الموضوعات: Chemistry; Acrylamide derivatives; Trifluoromethylpyridine
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/179399
• المؤسسة: Nanyang Technological University

In this study, a series of acrylamide derivatives containing trifluoromethylpyridine or piperazine fragments were rationally designed and synthesized. Subsequently, the in vitro antifungal activities of all of the synthesized compounds were evaluated. The findings revealed that compounds 6b, 6c, and...