Effects of HTLV-1 tax and CREB/ATF family of transcription factors on CMV MIE promoter in HEK293 cells.

• Main Author: Ko, Chen Wei.
• Other Authors: Chao Shu Ting Edlyn
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/18035
• Institution: Nanyang Technological University

The Human T-Lymphotropic virus type 1 (HTLV-1) genome codes for a 40 kD viral protein Tax which can trans activate the human cytomegalovirus (CMV) major immediate-early (MIE) enhancer in Jurkat T cells. The CMV MIE promoter is one of the strongest RNA polymerase II identified and is used industriall...