Single-cell laser emitting cytometry for label-free nucleolus fingerprinting

• Main Authors: Fang, Guocheng, Qiao, Zhen, Huang, Luqi, Zhu, Hui, Xie, Jun, Zhou, Tian, Xiong, Zhongshu, Su, I-Hsin, Jin, Dayong, Chen, Yu-Cheng
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2024
• Subjects: Engineering; Single cell analysis; Flow cytometry
• Online Access: https://hdl.handle.net/10356/180402
• Institution: Nanyang Technological University

The nucleolus, a recognized biomolecular condensate, serves as the hub for ribosome biogenesis within the cell nucleus. Its quantity and morphology are discernible indicators of cellular functional states. However, precise identification and quantification of nucleoli remain challenging without spec...