CREB-regulated transcription during glycogen synthesis in astrocytes

• Main Authors: Lim, Wei Lee, Gaunt, Jessica Ruth, Tan, Jia Min, Zainolabidin, Norliyana, Bansal, Vibhavari Aysha, Lye, Yi Ming, Ch'ng, Toh Hean
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Astrocyte; Vasoactive intestinal peptide
• Online Access: https://hdl.handle.net/10356/180436
• Institution: Nanyang Technological University

Glycogen storage, conversion and utilization in astrocytes play an important role in brain energy metabolism. The conversion of glycogen to lactate through glycolysis occurs through the coordinated activities of various enzymes and inhibition of this process can impair different brain processes incl...