Synergistic effect of ultrasound and reinforced electrical environment by bioinspired periosteum for enhanced osteogenesis via immunomodulation of macrophage polarization through Piezo1

• Main Authors: Jiang, Ting, Yu, Fei, Zhou, Yuqi, Li, Ruomei, Zheng, Mengting, Jiang, Yangyang, Li, Zhenxia, Pan, Jun, Ouyang, Ningjuan
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Physics; Piezoelectric periosteum; Electrical environment
• Online Access: https://hdl.handle.net/10356/180507
• Institution: Nanyang Technological University

The periosteum plays a vital role in repairing bone defects. Researchers have demonstrated the existence of electrical potential in the periosteum and native bone, indicating that electrical signals are essential for functional bone regeneration. However, the clinical use of external electrical trea...