Development of SERS active nanoprobe for selective adsorption and detection of Alzheimer's disease biomarkers based on molecular docking

• Main Authors: Garnaik, Umesh Chandra, Chandra, Anshuman, Goel, Vijay Kumar, Gulyás, Balázs, Padmanabhan, Parasuraman, Agarwal, Shilpi
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Alzheimer’s disease; Nanoparticles
• Online Access: https://hdl.handle.net/10356/180619
• Institution: Nanyang Technological University

Purpose: Development of SERS-based Raman nanoprobes can detect the misfolding of Amyloid beta (Aβ) 42 peptides, making them a viable diagnostic technique for Alzheimer’s disease (AD). The detection and imaging of amyloid peptides and fibrils are expected to help in the early identification of AD. Me...