Enzyme-responsive polyion complex nanoparticles of cationic antimicrobials for activatable antibacterial therapy

A self-assembled “caging” strategy is presented for the safe delivery of potent cationic antimicrobials that suffer from non-specific toxicity for the effective treatment of in vivo systemic bacterial infection. The key development here is a new block copolymer consisting of a poly(ethylene glycol)...

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Bibliographic Details
Main Authors: Zhang, Bo, Lu, Derong, Wang, Dennis Bao Rong, Kok, Zhi Yuan, Chan-Park, Mary B., Duan, Hongwei
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/180780
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Institution: Nanyang Technological University
Language: English