Benchmarking reverse docking through AlphaFold2 human proteome

• Main Authors: Luo, Qing, Wang, Sheng, Li, Hoi Yeung, Zheng, Liangzhen, Mu, Yuguang, Guo, Jingjing
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Human proteome; Reverse docking
• Online Access: https://hdl.handle.net/10356/180794
• Institution: Nanyang Technological University

Predicting the binding of ligands to the human proteome via reverse-docking methods enables the understanding of ligand's interactions with potential protein targets in the human body, thereby facilitating drug repositioning and the evaluation of potential off-target effects or toxic side effec...