Fighting fire with fire: phage discovery & characterisation to tackle antibiotic resistance crisis
Bacteriophages, also known as "phages”, are viruses with a DNA or RNA genome encased in a protein capsid. These viruses can replicate lytically or lysogenically. The lytic phages can infect bacteria specifically and use their cellular machinery to replicate and produce more phage particles, re...
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| Format: | Student Research Poster |
| Language: | English |
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Nanyang Technological University
2024
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| Online Access: | https://hdl.handle.net/10356/180861 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Bacteriophages, also known as "phages”, are viruses with a DNA or RNA genome encased in a protein capsid. These viruses can replicate lytically or lysogenically. The lytic phages can infect bacteria specifically and use their cellular machinery to replicate and produce more phage particles, resulting in bacterial cell lysis. With the rise in antibiotic resistant Klebsiella pneumoniae strains in Asia, it has rekindled interest in phage discovery and
characterisation since these lytic phages may be used as an alternative treatment for antibiotic-resistant infections. Hence, this study aims to isolate
Klebsiella phages with clinical significance from the environment and characterize them phenotypically and genotypically. |
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