Enantioselective reduction and sulfenylation of isoflavanone derivatives via bisguanidinium hypervalent silicate

• Main Authors: Li, Qiaoqiang, Dai, Yuqing, Xu, Xinru, Wu, Wentao, Chen, Wenchao, Wang, Hong, Tan, Choon-Hong, Ye, Xinyi
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Chemistry; Electrophilicity; Enantioselectivity
• Online Access: https://hdl.handle.net/10356/180956
• Institution: Nanyang Technological University

In this work, we describe an enantioselective reduction and sulfenylation of isoflavanone derivatives by an ion pair strategy. The chiral cationic catalyst bisguanidinium (BG) is capable of chiral induction in catalytic systems. Silane hydride works as a reductant and helps to form an anionic hyperv...