In-vitro validation of potential modulators of non-alcoholic fatty liver disease (NAFLD)

• Main Author: Tang, Daryl Woon Tat
• Other Authors: Torsten Wuestefeld
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2024
• Subjects: Medicine, Health and Life Sciences; Non-alcoholic fatty liver disease
• Online Access: https://hdl.handle.net/10356/181271
• Institution: Nanyang Technological University

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver injury, compromising the liver’s regenerative ability and promoting fibrosis. Despite its widespread impact, therapeutic options remain limited. The only FDA-approved drug for NASH, Rezdiffra, had limited efficacy in pat...