Dual beam optical coherence tomography angiography for decoupling axial velocity gradient
Axial velocity gradient (AVG) in the optical coherence tomography angiography (OCTA) signal affects measurement accuracy when the flow is not perpendicular to the scanning beam. We developed a dual beam OCTA method to decouple the contribution of AVG from the decorrelation signal. Decoupling is firs...
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sg-ntu-dr.10356-1813042024-11-25T02:08:15Z Dual beam optical coherence tomography angiography for decoupling axial velocity gradient Xu, Zhengyang Wang, Yukun Chen, Xi Lin, Kan Liu, Linbo School of Electrical and Electronic Engineering Engineering Optical coherence tomography angiography Optics Axial velocity gradient (AVG) in the optical coherence tomography angiography (OCTA) signal affects measurement accuracy when the flow is not perpendicular to the scanning beam. We developed a dual beam OCTA method to decouple the contribution of AVG from the decorrelation signal. Decoupling is first verified by phantom experiments which reduces measurement uncertainty from 1.5 to 0.7% (standard deviation). We also tested the method in human skin in vivo and the results indicate that the contribution of AVG to decorrelation signal is reduced. Ministry of Education (MOE) Ministry of Health (MOH) National Medical Research Council (NMRC) Published version This research is supported by the Singapore Ministry of Health’s National Medical Research Council under its Open Fund Individual Research Grant (MOH-OFIRG19may-0009), Ministry of Education Singapore under its Academic Research Fund Tier 1 (RG35/22) and its Academic Research Funding Tier 2 (MOE-T2EP30120-0001). 2024-11-25T02:08:15Z 2024-11-25T02:08:15Z 2024 Journal Article Xu, Z., Wang, Y., Chen, X., Lin, K. & Liu, L. (2024). Dual beam optical coherence tomography angiography for decoupling axial velocity gradient. Scientific Reports, 14(1), 19464-. https://dx.doi.org/10.1038/s41598-024-68924-4 2045-2322 https://hdl.handle.net/10356/181304 10.1038/s41598-024-68924-4 39174584 1 14 19464 en MOH-OFIRG19may-0009 RG35/22 MOE-T2EP30120-0001 Scientific Reports © 2024 The Author(s). Open Access. This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/ licenses/by-nc-nd/4.0/. application/pdf |
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Asia |
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Singapore Singapore |
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English |
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Engineering Optical coherence tomography angiography Optics |
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Engineering Optical coherence tomography angiography Optics Xu, Zhengyang Wang, Yukun Chen, Xi Lin, Kan Liu, Linbo Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| description |
Axial velocity gradient (AVG) in the optical coherence tomography angiography (OCTA) signal affects measurement accuracy when the flow is not perpendicular to the scanning beam. We developed a dual beam OCTA method to decouple the contribution of AVG from the decorrelation signal. Decoupling is first verified by phantom experiments which reduces measurement uncertainty from 1.5 to 0.7% (standard deviation). We also tested the method in human skin in vivo and the results indicate that the contribution of AVG to decorrelation signal is reduced. |
| author2 |
School of Electrical and Electronic Engineering |
| author_facet |
School of Electrical and Electronic Engineering Xu, Zhengyang Wang, Yukun Chen, Xi Lin, Kan Liu, Linbo |
| format |
Article |
| author |
Xu, Zhengyang Wang, Yukun Chen, Xi Lin, Kan Liu, Linbo |
| author_sort |
Xu, Zhengyang |
| title |
Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| title_short |
Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| title_full |
Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| title_fullStr |
Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| title_full_unstemmed |
Dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| title_sort |
dual beam optical coherence tomography angiography for decoupling axial velocity gradient |
| publishDate |
2024 |
| url |
https://hdl.handle.net/10356/181304 |
| _version_ |
1816859032127799296 |