Evaluating quasi-experimental approaches for estimating epidemiological efficacy of non-randomised field trials: applications in Wolbachia interventions for dengue

• Main Authors: Chow, Jo Yi, Geng, Lin, Bansal, Somya, Dickens, Borame Sue Lee, Ng, Lee Ching, Hoffmann, Ary Anthony, Lim, Jue Tao
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Wolbachia; Dengue
• Online Access: https://hdl.handle.net/10356/181312
• Institution: Nanyang Technological University

Background: Wolbachia symbiosis in Aedes aegypti is an emerging biocontrol measure against dengue. However, assessing its real-world efficacy is challenging due to the non-randomised, field-based nature of most intervention studies. This research re-evaluates the spatial–temporal impact of Wolbachia...